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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYBL2 All Species: 22.73
Human Site: T405 Identified Species: 38.46
UniProt: P10244 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10244 NP_002457.1 700 78764 T405 V G G S G I G T P P S V L K R
Chimpanzee Pan troglodytes XP_514658 769 86303 T405 V G G S G I G T P P S V L K R
Rhesus Macaque Macaca mulatta XP_001084853 700 78675 T405 V G G S G I G T P P S V L K R
Dog Lupus familis XP_534424 883 97262 T588 V G G L G I G T P P S V L K R
Cat Felis silvestris
Mouse Mus musculus P48972 704 79084 T408 F G G S G I G T P P S V L K R
Rat Rattus norvegicus NP_001100006 704 79549 T409 F G G S G I G T P P S V L K R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511778 753 85883 F441 T S P N E V K F S T P P T I L
Chicken Gallus gallus Q03237 686 77718 P388 E V S F G T P P S V L K R Q K
Frog Xenopus laevis P52551 743 82891 L408 K S T P V K S L P F S P S Q F
Zebra Danio Brachydanio rerio NP_001003867 633 70853 P362 R R R I A L S P D P N D S M T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797351 686 76826 T411 S T L N T P N T S R Y K T P Q
Poplar Tree Populus trichocarpa
Maize Zea mays P20024 340 36221 R69 Y L R P D L K R G N F T D E E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S7G7 776 86488 D477 D S L L P R N D S N A P I Q G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa O13493 324 36522 Q53 Q C R E R W H Q N L K P G L N
Conservation
Percent
Protein Identity: 100 88 98.2 72.5 N.A. 85.2 87.7 N.A. 38.3 72.5 54.2 52.1 N.A. N.A. N.A. N.A. 37.8
Protein Similarity: 100 89.7 98.7 74.7 N.A. 89.4 91.3 N.A. 54.5 81.5 69 65.8 N.A. N.A. N.A. N.A. 54
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 0 6.6 13.3 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 13.3 20 20 20 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. 20.1 N.A. 25.5 N.A. 20.7
Protein Similarity: N.A. 31.8 N.A. 40.8 N.A. 29.5
P-Site Identity: N.A. 0 N.A. 0 N.A. 0
P-Site Similarity: N.A. 13.3 N.A. 20 N.A. 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 0 0 0 0 8 0 0 0 0 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 8 0 0 8 8 0 0 8 8 0 0 % D
% Glu: 8 0 0 8 8 0 0 0 0 0 0 0 0 8 8 % E
% Phe: 15 0 0 8 0 0 0 8 0 8 8 0 0 0 8 % F
% Gly: 0 43 43 0 50 0 43 0 8 0 0 0 8 0 8 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 43 0 0 0 0 0 0 8 8 0 % I
% Lys: 8 0 0 0 0 8 15 0 0 0 8 15 0 43 8 % K
% Leu: 0 8 15 15 0 15 0 8 0 8 8 0 43 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 0 15 0 0 15 0 8 15 8 0 0 0 8 % N
% Pro: 0 0 8 15 8 8 8 15 50 50 8 29 0 8 0 % P
% Gln: 8 0 0 0 0 0 0 8 0 0 0 0 0 22 8 % Q
% Arg: 8 8 22 0 8 8 0 8 0 8 0 0 8 0 43 % R
% Ser: 8 22 8 36 0 0 15 0 29 0 50 0 15 0 0 % S
% Thr: 8 8 8 0 8 8 0 50 0 8 0 8 15 0 8 % T
% Val: 29 8 0 0 8 8 0 0 0 8 0 43 0 0 0 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _